A study published in the Journal of Neuroscience and supported by grants from the National Institutes of Health and Autism Speaks has found that the loss of a specific mutated gene in the auditory cortical neurons – the powerhouses of the sound-processing center – causes hypersensitive to sound. While the functioning PTEN gene is known for it’s anti-cancer roll in powering down cell growth, proliferation, and survival, a mutated version of PTEN has the opposite effect and has been found in autistic individuals with macroencephaly, or an increase in brain volume. Previous work with the mutated form of PTEN in mice has resulted in boosted cell size and number of neurological connections in the brain.
Gene Mutation in Autism Causes Hypersensitivity
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